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Enhanced response of the fricke solution doped with hematoporphyrin under X-rays irradiation BABT
Austerlitz,Carlos; Souza,Vivianne Lúcia Bormann de; Campos,Diana Maria Tavares; Kurachi,Cristina; Bagnato,Vanderley; Sibata,Cláudio.
The vials filled with Fricke solutions were doped with increasing concentrations of Photogem®, used in photodynamic therapy. These vials were then irradiated with low-energy X-rays with doses ranging from 5 to 20 Gy. The conventional Fricke solution was also irradiated with the same doses. The concentration of ferric ions for the Fricke and doped-Fricke irradiated solutions were measured in a spectrophotometer at 220 to 340 nm. The results showed that there was an enhancement in the response of the doped-Fricke solution, which was proportional to the concentration of the photosensitizer. The use of such procedure for studying the radiosensitizing property of photosensitizers based on the production of free radicals is also discussed.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Photodynamic therapy; Hematoporphyrin; Fricke dosimeter; Free radicals.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000200006
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The use of fricke dosimetry for low energy x-rays BABT
Austerlitz,Carlos de; Souza,Viviane; Villar,Heldio Pereira; Cordilha,Aloisio.
The performance of four X-ray qualities generated in a Pantak X-ray machine operating at 30-100 kV was determined with a parallel-plate ionization chamber and a Fricke dosimeter. X-ray qualities used were those recommended by Deutsch Internationale Normung DIN 6809 and dose measurements were carried out with Plexiglas® simulators. Results have shown that the Fricke dosimeter can be used not only for soft X-ray dosimetry, but also for the maintenance of low-energy measuring systems' calibration factor.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Radiation dosimetry; Soft X-rays; Fricke dosimeter.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132006000200004
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